1. A series of 1337 obstetric cases, of which 170 were instances of sensitized Rh negative women, were studied with regard to (a) the incidence of the ABO blood groups, and (b) the incidence of ABO compatibility between the mother and child.

2. The incidence of ABO compatibility between the mother and child was found to vary with the blood group of the mother.

3. ABO compatibility between the mother and child was found to be present in 80 per cent of an unselected obstetric population in contrast to 95 per cent in a group of sensitized Rh negative women who bore infants afflicted with hemolytic disease of the newborn.

4. ABO compatibility appears to be related to the occurrence of hemolytic disease of the newborn.

5. In 120 sensitized Rh negative women who bore afflicted infants, the incidence of group A mothers was greater than expected.

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