A simple method is described for isolating living polymorphonuclear leukocytes from peripheral blood. It is based on the selective adherence of these cells to a microscope slide, which permits all other blood components to be removed by washing. The reasons for considering this method useful in cell studies are discussed.

ACKNOWLEDGMENT The authors are indebted to Mr. Martin Shames and the King-Weese Studios, New York, for the photomicrograph.

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