A morphologic study of normal and AET-treated lymphocytes exposed in vitro to cytotoxic antibody and complement (C) has been carried out using both transmission and scanning electron microscopy. The abnormalities observed were of the same kind for the two types of cell, but they were more marked in AET-treated lymphocytes than in their untreated counterparts. These results confirm the serologic finding that AET-treated lymphocytes possess a higher than normal susceptibility to the damaging action of antibody and C in the lymphocytotoxicity reaction.

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© 1971 by American Society of Hematology, Inc.
1971
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