Platelet glycogen was studied under various conditions of ultracentrifugation and an isolation procedure devised.

Glycogen could be separated from the majority of soluble protein and cellular particulates by centrifugation into dense sucrose solutions. Minor contaminants were removed by differential centrifugation and detergent treatment. Characteristics of the isolated particles were consistent with the presumed "native" particle (glycosome) as measured by spectrophotometry, analytical ultracentrifugation, and protein: glycogen ratios.

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© 1970 by American Society of Hematology, Inc.
1970
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