Mice injected with a single, large dose of a bacterial endotoxin displayed a significant shift in erythropoiesis from the bone marrow to the spleen. Splenic granulocytopoiesis also occurred. This finding may have some bearing on the observation that endotoxin pretreated mice make a better recovery following x-irradiation than do their controls.

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© 1966 by American Society of Hematology, Inc.
1966
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