Brief Report: The Early Loss of Radioactivity in Cr⁵¹ Survival Curves: Destruction of Cells or Loss of the Label?

Using human erythrocytes labeled simultaneously with DFP³² and Cr⁵¹, studies of specific red cell activities within the first 24 hours after infusion of labeled cells were carried out. The results obtained suggest that the early loss of Cr⁵¹ specific red cell activity which has been observed in radiochromium survival curves is due to rapid elution of a portion of the label.