Antigens were demonstrated in platelets which were not detectable in plasma. One of these antigens was detected in serum and was presumed to be released during the process of coagulation. Plasminogen and fibrinogen were detected in platelets, and the fibrinogen appears to be part of the intracellular structure. Thrombin was found to act not only on fibrinogen but also on at least one other unidentified platelet protein.

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