Survival data were calculated for 125 patients with chronic lymphatic leukemia seen at the University of Minnesota Hospitals during the years 1945 to 1957 and followed for another 4 years. An actuarial method and modified maximum likelihood method were used for the statistical analyses.

The survival times in this study are significantly longer than those reported previously in large reference series of chronic leukemia. They more nearly approximate the results reported by Osgood for patients treated by his method of total body irradiation. It is suggested that in a disease with a wide clinical spectrum such as chronic lymphatic leukemia, differences in survival may be mainly related to differences in the composition of the groups being studied.

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