Evidence is presented for the presence of the antigens of nine blood group systems on normoblasts. The antigen receptors are detected on all stages of normoblasts. The in vivo demonstration of gamma globulin coating the reticulocytes and the normoblasts of a patient with erythroblastosis fetalis and the normoblasts of a patient with autoimmune hemolytic anemia are discussed in relationship to the pathogenesis of the anemia in both conditions.

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