1. Autologous bone marrow infusions are able to save the lives of dogs lethally irradiated with Y90-DTPA.

2. In certain cases the autologous marrow was able to save the life of the Y90-DTPA-irradiated dogs without any marked early elevation in circulating formed blood elements.

3. In contrast to results obtained using external irradiation technics, animals treated with Y90-DTPA and autologous marrow did not show early return of circulating lymphocytes.

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