Pediatric Hodgkin’s Lymphoma: 5-Year Experience at Single Center in Pakistan

OBJECTIVES:

To review patients’ characteristics and treatment outcome pattern of pediatric hodgkinlympoma in a well funded center in developing country

MATERIALS & METHOD: This was retrospective review of data of 301 pediatric hodgkin lymphoma patients up to 18 years of age treated in Shaukat Khanum Memeorial Cancer Hospital & Research Center, Lahore, Pakistan, during 2009 to 2013.

RESULTS:

Total No. of patients was 301, 81% were male. The median age of studied data was 9 years; ranging from 2 to 18 years. B symptoms in the form of fever, weight loss and night sweats were found in 51%, 29% and 34%, respectively. Median stage was 3 with neck bulky disease in 28% and Medistinal widening in 18% of patients. Trend of histopathology was mixed cellualrity at 56.5%. Most common treatment regime was ChlVPP/ABVD (59.5%); 30.6% of these 301 patient also got radiotherapy. At the end of treatment complete response was reported in 76.5%; 11.3% of these were relapsed afterward.

CONCLUSION:

Our data shows excellent outcome of pediatric hodgkin lympoma and results are comparable to that of developed countries.