Li H, Malani N, Hamilton SR, et al. Assessing the potential for AAV vector genotoxicity in a murine model. Blood. 2011;117(12):3311–3319. Free

On pages 3311 and 3314 in the 24 March 2011 issue, the word “cysteine” should be “cytosine.” In the “Abstract” on page 3311, the seventh sentence read, “Integration patterns in tumor tissue and adjacent normal tissue were similar to each other, showing preferences for active genes, cytosine-phosphate-guanosine islands, and guanosine/cysteine-rich regions.” The correct sentence should have read: “Integration patterns in tumor tissue and adjacent normal tissue were similar to each other, showing preferences for active genes, cytosine-phosphate-guanosine islands, and guanosine/cytosine-rich regions.” In “Results,” under the heading “Profiling of AAV2-hFIX16 vector integration sites,” the second sentence of the third paragraph on page 3314 read, “In normal liver tissue there was a preference for integrating near genes (P < .001), CpG islands (P < .05), and guanosine/cysteine-rich (G-C rich) regions (P < .05) (Figure 2B).” The correct sentence should have read: “In normal liver tissue there was a preference for integrating near genes (P < .001), CpG islands (P < .05), and guanosine/cytosine-rich (G-C rich) regions (P < .05; Figure 2B).”