Tjwa et al. Plasmin therapy enhances mobilization of HPCs after G-CSF. Blood. 2008;112:4048-4050.

On page 4049 in the November 15, 2008, issue, the second and third sentences of the second paragraph under the heading “Thrombolytic agents enhance HPC mobilization after G-CSF” contain incorrect information.

The correct sentences should read: “Nonetheless, daily intraperitoneal bolus injection of human rtPA (100 mg/kg) for 5 days failed to enhance HPC mobilization or increase leukocytosis in steady-state conditions or following G-CSF administration in mice (not shown). Heissig et al reported that a 10-fold lower dose of human rtPA in mice increases leukocytosis after myeloablation¹⁰; the precise reason for this variance remains unexplained, but might be related to the different experimental conditions (G-CSF versus myeloablation).”