Topics:
regulatory t-lymphocytes

On page427 in the July 15, 2006, issue there is an error in Figure 1. CXCL19 should be CCL19. The corrected figure is shown.

Figure 1
Figure 1. Organ/tissue trafficking and distribution of Treg cells. Distinct chemokine receptors and integrin molecules implicated in Treg-cell organ/tissue trafficking and compartmentalization are presented. Bone marrow–derived CXCL12 mediates Treg-cell bone marrow trafficking. Environmental CCL22 mediates Treg-cell trafficking into human ovarian cancer and mouse cardiac grafts. The lymphoid homing molecules CCR7 and CD62L may facilitate lymphoid homing of Treg cells. Certain CC chemokines and integrins may mediate Treg-cell trafficking into inflammatory tissues/organs.
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Organ/tissue trafficking and distribution of Treg cells. Distinct chemokine receptors and integrin molecules implicated in Treg-cell organ/tissue trafficking and compartmentalization are presented. Bone marrow–derived CXCL12 mediates Treg-cell bone marrow trafficking. Environmental CCL22 mediates Treg-cell trafficking into human ovarian cancer and mouse cardiac grafts. The lymphoid homing molecules CCR7 and CD62L may facilitate lymphoid homing of Treg cells. Certain CC chemokines and integrins may mediate Treg-cell trafficking into inflammatory tissues/organs.

Figure 1
Figure 1. Organ/tissue trafficking and distribution of Treg cells. Distinct chemokine receptors and integrin molecules implicated in Treg-cell organ/tissue trafficking and compartmentalization are presented. Bone marrow–derived CXCL12 mediates Treg-cell bone marrow trafficking. Environmental CCL22 mediates Treg-cell trafficking into human ovarian cancer and mouse cardiac grafts. The lymphoid homing molecules CCR7 and CD62L may facilitate lymphoid homing of Treg cells. Certain CC chemokines and integrins may mediate Treg-cell trafficking into inflammatory tissues/organs.
View largeDownload PPT

Organ/tissue trafficking and distribution of Treg cells. Distinct chemokine receptors and integrin molecules implicated in Treg-cell organ/tissue trafficking and compartmentalization are presented. Bone marrow–derived CXCL12 mediates Treg-cell bone marrow trafficking. Environmental CCL22 mediates Treg-cell trafficking into human ovarian cancer and mouse cardiac grafts. The lymphoid homing molecules CCR7 and CD62L may facilitate lymphoid homing of Treg cells. Certain CC chemokines and integrins may mediate Treg-cell trafficking into inflammatory tissues/organs.

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© 2008 by The American Society of Hematology
2008
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