Abstract
Severe factor XI (FXI) deficiency is an injury related bleeding tendency. Fresh frozen plasma (FFP) or FXI concentrate are usually used for achieving hemostasis in such patients undergoing surgery but this can lead to inhibitor formation in 33% of patients with FXI level <1 U/dL (
Blood
101
:4783
, 2002
NEJM
325
:153
, 1991
SITE OF SURGERY . | N . | BLEEDERS . | % BLEEDERS . |
---|---|---|---|
Non-fibrinolytic | |||
Appendicectomy | 22 | 1 | 1.6 |
Gastric | 3 | 0 | 0 |
Cholecystectomy | 5 | 1 | 20 |
Herniotomy | 13 | 3 | 23 |
Hysterectomy | 5 | 2 | 40 |
Orthopedic | 9 | 0 | 0 |
Fibrinolytic | |||
Tonsillectomy | 33 | 20 | 60.6 |
Nose | 12 | 7 | 58.3 |
Prostatectomy | 3 | 2 | 66.6 |
Circumcision | |||
64 | 1 | 1.6 | |
Oral | |||
Tooth extractions | 100 | 49 | 49 |
Gum | 10 | 6 | 60 |
SITE OF SURGERY . | N . | BLEEDERS . | % BLEEDERS . |
---|---|---|---|
Non-fibrinolytic | |||
Appendicectomy | 22 | 1 | 1.6 |
Gastric | 3 | 0 | 0 |
Cholecystectomy | 5 | 1 | 20 |
Herniotomy | 13 | 3 | 23 |
Hysterectomy | 5 | 2 | 40 |
Orthopedic | 9 | 0 | 0 |
Fibrinolytic | |||
Tonsillectomy | 33 | 20 | 60.6 |
Nose | 12 | 7 | 58.3 |
Prostatectomy | 3 | 2 | 66.6 |
Circumcision | |||
64 | 1 | 1.6 | |
Oral | |||
Tooth extractions | 100 | 49 | 49 |
Gum | 10 | 6 | 60 |
Author notes
Corresponding author
2005, The American Society of Hematology
2005
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