Erratum for vol. 97, p. 2130

doi:10.1182/blood.V97.11.3678.h8003678_3678_3678

In the article entitled “Kaposi sarcoma-associated herpesvirus infects monotypic (IgMγ) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders,” which appeared in the April 1, 2001, issue of Blood(97:2130-2136), Tables 3 and 4 should have appeared as follows.

2001

Table 3.

Sequence analysis of the rearranged IgH gene in KSHV-positive cells

Case no.	Lesion	Total no. of clones	Clones with identical V_H	Clones with identical CDR3	Mutation in V_H
1	Lymphoma (LN)	8	8 (DP75)	5	1s

	Microlymphoma 1 (Sp)	8	5 (DP14)	4	1s
			1 (DP75)	Identical to the dominant lymphoma clone	1s

			4 (DP10)	2	1R
	Microlymphoma 2 (Sp)	9	3 (DP14)		1s
			1 (DP75)	Identical to the dominant lymphoma clone	1s

			2 (V3-64)	2	—
			2 (DP77)	2	1R
			1 (DP49)		—
	Microlymphoma 1 (Sp)	8	1 (DP47)		2R
			1 (V3-53)		1R
			1 (Cos-8)		—

			3 (DP47)	2	—
			2 (DP77)		—
2	Microlymphoma 2 (Sp)	10	2 (DP38)		—
			1 (DP54)		—
			1 (DP53)		2s

			3 (DP42)		—
			2 (8−1B+)		1s
	Microlymphoma 3 (Sp)	8	1 (DP58)		—
			1 (DP63)		—
			1 (Cos-8)		1R, 1s

			2 (DP71)	2	3s
			3 (DP77)		2R
			1 (DP49)		1s
3	Microlymphoma 1 (LN)	10	2 (DP47)		—
			1 (V3-64)		1R
			1 (DP54)		1R

			3 (DP49)		—
			2 (DP47)		—
	Microlymphoma 2 (LN)	7	1 (DP63)		1R
			1 (4.30)		1R

			4 (DP78)	4	—
4	Micro-lymphoma 1 (Sp)	10	3 (DP46)	3	1R
			1 (DP47)		—

Case no.	Lesion	Total no. of clones	Clones with identical V_H	Clones with identical CDR3	Mutation in V_H
1	Lymphoma (LN)	8	8 (DP75)	5	1s

	Microlymphoma 1 (Sp)	8	5 (DP14)	4	1s
			1 (DP75)	Identical to the dominant lymphoma clone	1s

			4 (DP10)	2	1R
	Microlymphoma 2 (Sp)	9	3 (DP14)		1s
			1 (DP75)	Identical to the dominant lymphoma clone	1s

			2 (V3-64)	2	—
			2 (DP77)	2	1R
			1 (DP49)		—
	Microlymphoma 1 (Sp)	8	1 (DP47)		2R
			1 (V3-53)		1R
			1 (Cos-8)		—

			3 (DP47)	2	—
			2 (DP77)		—
2	Microlymphoma 2 (Sp)	10	2 (DP38)		—
			1 (DP54)		—
			1 (DP53)		2s

			3 (DP42)		—
			2 (8−1B+)		1s
	Microlymphoma 3 (Sp)	8	1 (DP58)		—
			1 (DP63)		—
			1 (Cos-8)		1R, 1s

			2 (DP71)	2	3s
			3 (DP77)		2R
			1 (DP49)		1s
3	Microlymphoma 1 (LN)	10	2 (DP47)		—
			1 (V3-64)		1R
			1 (DP54)		1R

			3 (DP49)		—
			2 (DP47)		—
	Microlymphoma 2 (LN)	7	1 (DP63)		1R
			1 (4.30)		1R

			4 (DP78)	4	—
4	Micro-lymphoma 1 (Sp)	10	3 (DP46)	3	1R
			1 (DP47)		—

Clones with frequent mutations (> 10) were occasionally seen. They are most likely from reactive B cells rather than KSHV-positive plasmablasts and are not included.

S indicates silent mutation; R, replacement change; —, no mutation; LN, lymph node; Sp, spleen.

Table 4.

Sequence analysis of the rearranged Igλ gene in KSHV-positive cells

Case no.	Lesion	Total no. of clones	Clones with identical Vλ	Clones with identical CDR3	Mutation in Vλ
			6 (DPL11)	6	1s
			1 (DPL15)		1R
	Lymphoma (LN)	10	1 (DPL8)		1R
			1 (DPL18)		—

1			5 (DPL3)		1s
			3 (DPL19)	3	1s
	Microlymphoma 1 (Sp)	17	3 (DPL11)	3 identical to the dominant lymphoma clone	2R
			1 (DPL3)		—
			1 (G7)		—
			1 (DPL5)		2R, 1s

Case no.	Lesion	Total no. of clones	Clones with identical Vλ	Clones with identical CDR3	Mutation in Vλ
			6 (DPL11)	6	1s
			1 (DPL15)		1R
	Lymphoma (LN)	10	1 (DPL8)		1R
			1 (DPL18)		—

1			5 (DPL3)		1s
			3 (DPL19)	3	1s
	Microlymphoma 1 (Sp)	17	3 (DPL11)	3 identical to the dominant lymphoma clone	2R
			1 (DPL3)		—
			1 (G7)		—
			1 (DPL5)		2R, 1s

Clones with frequent mutations (> 5) were occasionally seen. They are most likely from reactive B cells rather than KSHV-positive plasmablasts and are not included.

S indicates silent mutation; R, replacement change; —, no mutation; LN, lymph node; Sp, spleen.

Erratum for vol. 97, p. 2130

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Erratum for vol. 97, p. 2130

Contents

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Supplemental data

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ASH Publications

American Society of Hematology

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