Proteolytic and Fibrinolytic Activity of Serum : Activation by Streptokinase and Staphylokinase Indicating Dissimilarity of Enzymes

1. The fibrinolytic and proteolytic activity of serum plasminogen, activated by Streptokinase and Staphylokinase and measured by clot lysis and casein digestion, was studied in the following species of animals: human, cow, dog, horse, monkey, pig, rabbit, rat, and chicken.

2. A significant difference in fibrinolytic and proteolytic activity of serum plasminogen (activated by staphylokinase) was observed in three animal species: monkey, horse, and human. The significance of this observation is briefly discussed.