When used in equimolar concentrations, five different calcium-combining anticoagulants produced uniform dilution of a given blood sample.

The potassium anticoagulants seem to exert a hemolytic effect on the erythrocytes.

The plasma dilution caused by a given concentration of the calcium-combining anticoagulants ranged from 8 to 20 per cent in the bloods examined. This shows the importance of using serum or unoxalated plasma for comparing the plasma protein concentrations of individual blood samples.

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