A patient with an atypical myeloproliferative syndrome characterized by leukocytosis with myeloid immaturity, ineffective extramedullary erythropoiesis, overt hemolysis and low leukocyte alkaline phosphatase activity demonstrated a trisomy in the C group of bone marrow metaphase chromosomes.

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© 1966 by American Society of Hematology, Inc.
1966
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