A case of an unusual lymphomatous disease associated with lymphoplasmocytoid cells containing intracytoplasmic crystals is presented. These crystals are considered to be the secretory product of these cells. They are discussed in the light of recent studies on the secretory activity of plasmocytes and related cells.

A specific diagnosis of the patient's disease is not made although the main cell type present closely resembles that occurring in Waldenström’s macroglobulinemia.

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