Abstract
The first component of the complement (C) system C1q has multiple immune functions including acting as a chemoattractant for mature blood cells, and it has recently been reported that hematopoietic stem/progenitor cells (HSPC) express the C1q receptor, C1qRp. We have reported that the complement components C3 and C5 play an important role in the mobilization of HSPC and that G-CSF mobilization activates C by the classical Ig-dependent pathway (
Blood
2004
;103
:2071
Author notes
Disclosure: No relevant conflicts of interest to declare.
2007, The American Society of Hematology
2007