Abstract
We have previously described a patient with platelet phospholipase C (PLC)-β2 deficiency characterized by impaired platelet responses to activation with multiple G-protein coupled receptor agonists. The PLC-β2 coding sequence was normal and platelet PLC-β2 mRNA levels were decreased in the patient (
Blood
, 2002
, 99
:905
Disclosure: No relevant conflicts of interest to declare.
2006, The American Society of Hematology
2006