Abstract
The Cooperative Study of Sickle Cell Disease (CSSCD) reported that dactylitis, severe anemia, and leukocytosis in very young children with SCD increased the risk of later adverse outcomes, including death, stroke, recurrent acute chest syndrome (ACS), and frequent pain (
NEJM
2000
;342
:83
Blood
2004
;103
:4023
Disclosure: No relevant conflicts of interest to declare.
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2006, The American Society of Hematology
2006