A man in his 30s with primary mediastinal B-cell lymphoma began chemotherapy with dose-adjusted rituximab, etoposide, prednisolone, vincristine, cyclophosphamide, and doxorubicin (DA-R-EPOCH protocol). After the fourth cycle, asymptomatic hyperpigmented macules were noted on the patient’s tongue (Figure).
What is the diagnosis?
Black hairy tongue
Melanocytic nevi
Drug-induced pigmentation
Primary adrenal insufficiency
Pigmented fungiform papillae
For the solution to the quiz, visit The Hematologist online, https://ashpublications.org/thehematologist/pages/hyperpigmentation_of_the_tongue_in_a_patient_with_lymphoma.
Competing Interests
Dr. Suárez, Dr. López-García, and Dr. Solán indicated no relevant conflicts of interest.
