Local African ancestry of responders and nonresponders. (A) Local ancestry across chromosome 11 in cases and controls shows a strong peak of African ancestry at the HBB locus. (B-C) local African ancestry on chromosomes 2 and 5 in responders (cases) and nonresponders (controls). At each locus mean values are plotted as a bold line, with shaded values indicating upper (95%) and lower (5%) CIs.