Figure 1: The Fab of Conventional Antibodies Bind to Their Target Cells but do not Bind to T Cells as T Cells Lack a Receptor for the Fc Portion of the Antibody. BiTE antibody-like molecule is a single-chain polypeptide consisting of a binding site for the target antigen and a CD3 binding site that binds to CD3.

Figure 1: The Fab of Conventional Antibodies Bind to Their Target Cells but do not Bind to T Cells as T Cells Lack a Receptor for the Fc Portion of the Antibody. BiTE antibody-like molecule is a single-chain polypeptide consisting of a binding site for the target antigen and a CD3 binding site that binds to CD3.

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