Eight genomic categories of myeloproliferative neoplasms (MPNs): classification schematic, distribution with MPN subtypes, outcomes in chronic disease (polycythemia vera [PV] or essential thrombocythemia [ET]), and outcomes in myelofibrosis (either primary myelofibrosis or post-PV/ET myelofibrosis [MF]). (Reprinted from Grinfeld J, Nangalia J, Baxter EJ, et al. Classification and Personalized Prognosis in Myeloproliferative Neoplasms. N Engl J Med. 2018;379:1416-1430.)