Treatment Schema. Inotuzumab ozogamicin dose reduced to 1.5 mg/m2/cycle once complete remission/complete remission with incomplete hematologic recovery was achieved. Abbreviations: ALL, acute lymphocytic leukemia; FLAG, fludarabine, cytarabine, and granulocyte colony-stimulating factor. Adapted with permission from N Engl J Med. 2016;375:740-753.