Cytogenetic, Copy Number, and Mutational Profile of Relapsed Acute Lymphoblastic Leukemia Patients Stratified by Clinical Risk Group. Cytogenetic, copy number, and mutational profile of relapsed acute lymphoblastic leukemia patients stratified by clinical risk group. Frequency of individual chromosomal abnormalities, copy number alterations and sequence mutations among clinical standard and high-risk B-cell precursor ALL patients treated in ALLR3. *P<.05; **P< .01Reprinted with permission from Irving JAE, Enshaei A, Parker CA, et al. Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia. Blood. 2016;128:911-922.