American Society of Hematology

Figure 3.

$Hemostatic response to injury. Real-time confocal intravital microscopy following penetrating laser injuries in cremaster muscle arterioles in WT and RGS10−/−18−/− mice. (A) Representative end-point images of hemostatic plugs. Mean area of accumulation over time was measured for CD41 (αIIb integrin) (B), P-selectin (C), and fibrin (D). (E) Mean end-point area calculations. (F) The fraction of injuries that produced stable or transient occlusions. n = 52 injuries in 3 WT mice; n = 50 injuries in 4 RGS10−/−18−/− mice; mean ± SEM.$

Hemostatic response to injury. Real-time confocal intravital microscopy following penetrating laser injuries in cremaster muscle arterioles in WT and RGS10^−/−18^−/− mice. (A) Representative end-point images of hemostatic plugs. Mean area of accumulation over time was measured for CD41 (α_IIb integrin) (B), P-selectin (C), and fibrin (D). (E) Mean end-point area calculations. (F) The fraction of injuries that produced stable or transient occlusions. n = 52 injuries in 3 WT mice; n = 50 injuries in 4 RGS10^−/−18^−/− mice; mean ± SEM.

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