Figure 1.
Dietary supplementation of DGLA enhances DPAn-3and DPAn-6in mouse platelets. (A) Platelets (left panel) and platelet-rich plasma (PPP; right panel) from WT mice were measured for omega-3 and omega3 PUFAs (DGLA, AA, DPAn-6, DPAn-3, and DHA) following 1 month of daily dietary supplementation of 50 mg/kg of DGLA (n = 5) or polyethylene glycol 300 control (n = 3). The potency of DPAn-3 and DPAn-6 was determined by human platelets measuring aggregation in response to thrombin (B) or collagen (C) (n = 10). Data are means ± SEM. *P < .05, 1-way ANOVA.

Dietary supplementation of DGLA enhances DPAn-3and DPAn-6in mouse platelets. (A) Platelets (left panel) and platelet-rich plasma (PPP; right panel) from WT mice were measured for omega-3 and omega3 PUFAs (DGLA, AA, DPAn-6, DPAn-3, and DHA) following 1 month of daily dietary supplementation of 50 mg/kg of DGLA (n = 5) or polyethylene glycol 300 control (n = 3). The potency of DPAn-3 and DPAn-6 was determined by human platelets measuring aggregation in response to thrombin (B) or collagen (C) (n = 10). Data are means ± SEM. *P < .05, 1-way ANOVA.

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