Assessment of immunologic correlative studies. (A) Time course of major cell populations at baseline and through 2 years of alloHCT, including lymphocyte counts (PBL), total T cells (CD3⁺), CD4⁺ and CD8⁺ T cells, B cells (CD19⁺CD5⁻), NK cells (CD56⁺CD3⁻), and dendritic cells (HLA-DR⁺LINEAGE⁻). Each dot represents median value of absolute counts. (B) CD4Treg/CD4Tcon ratio over time. (C) CD4Treg and CD4Tcon median percentage of effector memory (EM), central memory (CM), naive and terminally differentiated (TD) cells. (D) Absolute counts of B cells (CD19⁺CD5⁻), antigen-naive B cells (CD19⁺CD5⁻27⁻), and antigen experienced B cells (CD19⁺CD5⁻27⁺). Each dot represents median value. *P < .05 and **P < .01 compared with the prior chemoimmunotherapy.