Log-transformed percentage of change in mean MBF with thermal stimulation in patients with SCD and controls. For all thermal stimuli, patients with SCD showed a significantly greater decrease in MBF (multivariate repeated-measures ANOVA, P = .019), as depicted on the y-axis. Patients with SCD had significantly higher PASS scores than controls (P = .013) as depicted on the x-axis. By multivariate analysis, the PASS score was a significant predictor of MBF response (P = .026). *Log₁₀ (x + 1) transformed data.