Figure 1.
Overview of IgG2a anti-MHC class I antibodies that either cause TRALI or are unable to cause TRALI in mice. BALB/c (left) and C57BL/6 (right) mice are depicted. Notably, a higher dose of 34-1-2S, compared with AF6-88.5.5.3 (10:1), is required to obtain TRALI in C57BL/6 mice. Antibody-mediated TRALI induction or resistance is based on published literature, as indicated in the text.

Overview of IgG2a anti-MHC class I antibodies that either cause TRALI or are unable to cause TRALI in mice. BALB/c (left) and C57BL/6 (right) mice are depicted. Notably, a higher dose of 34-1-2S, compared with AF6-88.5.5.3 (10:1), is required to obtain TRALI in C57BL/6 mice. Antibody-mediated TRALI induction or resistance is based on published literature, as indicated in the text.

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