Figure 1.
The proposed mechanism of action of ruxolitinib in aGVHD. Ruxolitinib interferes with cytokine sensing, cytokine production, recruitment of tissue-damaging myeloid cells, chemotaxis, MHC expression, and T-cell priming. IFN, interferon; IL, interleukin; P, phosphate; ROS, reactive oxygen species; Th17, T helper 17 cell.

The proposed mechanism of action of ruxolitinib in aGVHD. Ruxolitinib interferes with cytokine sensing, cytokine production, recruitment of tissue-damaging myeloid cells, chemotaxis, MHC expression, and T-cell priming. IFN, interferon; IL, interleukin; P, phosphate; ROS, reactive oxygen species; Th17, T helper 17 cell.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal