VWF and VWFpp levels were measured in plasma from the TwinsUK study. (A) VWF and (B) VWFpp levels were mean centered, log transformed, and adjusted for height, weight, and ABO blood type status predicted by genotype. STAB2^−/+ indicated individuals with 1 qualifying variant in STAB2 (N = 31), while STAB2^+/+ indicates individuals with no qualifying variant (n = 996). Black lines indicate interquartile range, and red line indicates median. P values for the difference in the distributions between STAB2^−/+ and ^+/+ individuals were calculated using the Mann-Whitney U test.