Survival curves for GCB vs ABC subtypes of DLBCL defined by previous classification methods and the new NGS-COO classifier. (A) Three subtypes defined by a 100-gene-classifier for gene-expression profiled cases using Affymetrix GeneChip. (B) GCB and ABC subtypes defined by a 100-gene-classifier and the Visco-Young IHC algorithm as described in "Patients and methods." (C) GCB and ABC subtypes defined by the new NGS-COO classifier.