Recurrent mutations are identified in MCL. (A) Mutations observed across 273 MCL samples in 18 candidate MCL genes. Mutations shown here are limited to nonsilent mutations of all genes with the exception of HNRNPH1. For this gene, intronic and silent mutations affecting or immediately surrounding exon 4 are included. Spatial distribution of mutations observed in (B) EWSR1, and (C) DAZAP1 in MCL compared with DLBCL.