Hematological and iron parameters of Hbb^th3/+mice with germ line deletion of Tfr2. Hematological parameters of both male and female Hbb^th3/+ mice with wt Tfr2 (Tfr2^+/+) or germ line ablation of a single allele (Tfr2^+/−) or both alleles (Tfr2^−/−) of Tfr2 determined at 10, 25, and 37 weeks of age; iron parameters were determined in a pool of 10- and 37-week-old Hbb^th3/+, Tfr2^+/−/Hbb^th3/+, and Tfr2^−/−/Hbb^th3/+ mice. In the figure are graphed: (A) RBC count; (B) Hb levels; (C) MCV; (D) MCH; (E) LIC, (F) TS, and (G) SIC. The dotted red line indicates mean value in wt IB mice. Error bars indicate SE. Asterisks refer to statistically significant differences: *P < .05; **P < .01; ***P < .005.