Flowchart for scaling of parameters of arterial thrombosis and thromboembolism. Scored were studies of in vivo arterial thrombus formation (class I), thromboembolism (class II), and in vitro thrombus formation (class III) for mice with a genetic modification (GM) or pharmacological treatment, in comparison with wild type (WT) or the control condition. Indicated are scaling rules (scores) for the various output parameters on 3- and 5-point scales (values for WT set at 100%). For detailed description of groups and scoring procedures, see supplemental Table 2.