Risk stratification: characteristics associated with increased TRM in patients MC-TA-TMA. Among the 110 patients MC-TA-TMA, the factors associated with increased TRM included the need for >2 antihypertensive medications (P = .0001, Gray’s test) (A), LDH >2 times the ULN (P = .0011, Gray’s test) (B), and AKI (P = .0034, Gray’s test) (C).