Figure 3.
RHOA mutational frequencies and haplotypes vary between individuals. Haplotypes at RHOA exon 2 from each PTCL case in which the baseline plasma sample contained a total RHOA mutational burden (VAF) >10%. The pie chart represents the proportions of each individual exon 2 mutation as a fraction of all reads bearing a RHOA mutation. Panels to the right show down-sampled read pileups (representing ∼10% of all reads) with the position of mutations indicated above and the DNA sequence below.

RHOA mutational frequencies and haplotypes vary between individuals. Haplotypes at RHOA exon 2 from each PTCL case in which the baseline plasma sample contained a total RHOA mutational burden (VAF) >10%. The pie chart represents the proportions of each individual exon 2 mutation as a fraction of all reads bearing a RHOA mutation. Panels to the right show down-sampled read pileups (representing ∼10% of all reads) with the position of mutations indicated above and the DNA sequence below.

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