B-ALL patients with TP53 mutation had a lower OS and LFS than those without TP53 mutation. (A-B) The 102 patients were divided into 2 groups based on TP53 mutation status: TP53⁺ mutation and TP53^– mutation. Kaplan-Meier analysis showed that OS and LFS at 6 months were much lower for patients carrying the TP53 mutation when compared with the patients without a TP53 mutation (OS: 51.9% vs 89.0%; P < .0001; HR, 61.75; 95% CI, 11.35-336.1; LFS: 42.4% vs 82.6%; P = .0002; HR, 0.06; 95% CI, 0.014-0.26).