MH in combination with NCCN-IPI or TMTV stratifies the risk of newly diagnosed DLBCL. Kaplan-Meier plots of OS (A) and EFS (B) in patients with NCCN-IPI high or high-intermediate. Kaplan-Meier plots of OS (C) and EFS (D) in 3 groups based on MH plus TMTV: low MH and low TMTV (n = 44), high MH or high TMTV (n = 54), and high MH and high TMTV (n = 52).