Figure 5.
Immunologic reconstitution of lymphocyte subsets in the first 6 months posttransplant for patients treated with and without NK cells. Immune subsets were determined by clinical flow cytometry. Absolute cell counts were calculated based on subset percentages and total WBC count obtained at the same time. Red, 2009-0266, previous clinical trial without NK cells; blue, 2012-0708, current phase 1 clinical trial. (A) Total WBC count. (B) Total lymphocyte count (CD3+). (C) CD56+CD3− NK cells. (D) CD3+CD4+ T cells. (E) CD3+CD8+ T cells. (F) CD3+CD25+ T-regulatory cells. (G) CD3+CD45RA+ naïve T cells. (H) CD+CD45RO+ memory T cells. (I) CD19+ B cells. D30, day 30 posttransplant; D90, day 90 posttransplant; day 180, day 180 posttransplant; WBC, total WBC count.

Immunologic reconstitution of lymphocyte subsets in the first 6 months posttransplant for patients treated with and without NK cells. Immune subsets were determined by clinical flow cytometry. Absolute cell counts were calculated based on subset percentages and total WBC count obtained at the same time. Red, 2009-0266, previous clinical trial without NK cells; blue, 2012-0708, current phase 1 clinical trial. (A) Total WBC count. (B) Total lymphocyte count (CD3+). (C) CD56+CD3 NK cells. (D) CD3+CD4+ T cells. (E) CD3+CD8+ T cells. (F) CD3+CD25+ T-regulatory cells. (G) CD3+CD45RA+ naïve T cells. (H) CD+CD45RO+ memory T cells. (I) CD19+ B cells. D30, day 30 posttransplant; D90, day 90 posttransplant; day 180, day 180 posttransplant; WBC, total WBC count.

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