CLL cells induce Vγ9Vδ2-T–cell dysfunction. Cytokine production (A) and CD107a expression (B) by HC Vγ9Vδ2-T cells after coculture with allogeneic healthy B cells or CLL cells for 36 hours at a 1:10 ratio and subsequent coculture with ABP-pretreated Daudi cells (n = 6). Cytokine production (C) and CD107a expression (D) by HC Vγ9Vδ2-T cells after coculture and subsequent stimulation with PMA/ionomycin (n = 6). Data are mean and SEM. *P < .05, **P < .01, ***P < .001, ****P < .0001, 1-way ANOVA, followed by the Bonferroni post hoc test.