Figure 3.
Figure 3. RFS and OS among Ph-positive patients in hematologic CR at start of treatment (key secondary end point full analysis set). (A) RFS without censoring at allogeneic HSCT or postblinatumomab chemotherapy. Median follow-up, 29.9 months. (B) RFS by remission status at screening without censoring at allogeneic HSCT or postblinatumomab chemotherapy. Complete MRD response was defined as MRD negativity with minimum sensitivity of 10−4. (C) OS without censoring at allogeneic HSCT or postblinatumomab chemotherapy. Median follow-up, 30.0 months. (D) OS by complete MRD responder status in cycle 1 among evaluable patients (landmark analysis, excluding patients who were censored or had relapsed or died within 45 days of beginning treatment), without censoring at allogeneic HSCT or postblinatumomab chemotherapy. (E) RFS without censoring at allogeneic HSCT or postblinatumomab chemotherapy by complete MRD responder status in cycle 1 and salvage status among evaluable patients (landmark analysis, excluding patients who were censored or had relapsed or died within 45 days of beginning treatment). NR, not reached.

RFS and OS among Ph-positivepatients in hematologic CR at start of treatment (key secondary end point full analysis set). (A) RFS without censoring at allogeneic HSCT or postblinatumomab chemotherapy. Median follow-up, 29.9 months. (B) RFS by remission status at screening without censoring at allogeneic HSCT or postblinatumomab chemotherapy. Complete MRD response was defined as MRD negativity with minimum sensitivity of 10−4. (C) OS without censoring at allogeneic HSCT or postblinatumomab chemotherapy. Median follow-up, 30.0 months. (D) OS by complete MRD responder status in cycle 1 among evaluable patients (landmark analysis, excluding patients who were censored or had relapsed or died within 45 days of beginning treatment), without censoring at allogeneic HSCT or postblinatumomab chemotherapy. (E) RFS without censoring at allogeneic HSCT or postblinatumomab chemotherapy by complete MRD responder status in cycle 1 and salvage status among evaluable patients (landmark analysis, excluding patients who were censored or had relapsed or died within 45 days of beginning treatment). NR, not reached.

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