Figure 1.
Growth inhibitory effects of HTLV-1–infected cell lines by MK-2048. (A) Viability of the indicated cells after treatment with IN inhibitors (50 or 100 μM). The CellTiter values of the treated cells relative to those of untreated cells are shown. The results are expressed as the mean ± SD of 3 independent experiments. (B) Viability of the indicated cells after treatment with MK-2048 (0 to 50 μM). The CellTiter values of the cells relative to the untreated cells are shown. The results are expressed as the mean ± SD of 3 independent experiments. (C) The IC50 values (μmol/L) of MK-2048 across 12 uninfected or HTLV-1–infected cell lines. Cells were treated for 72 hours.