Genetic alterations in TP53, TP63, and TP73 genes. (A) Mutations identified in TP53, TP63 and TP73 in HBsAg⁺ and HBsAg^- DLBCLs. (B-C) Diagram showing mutations identified in TP63 and TP73, respectively. (D) Alignment of the DNA-binding domain (DBD) of TP53, TP63, and TP73. OD, oligomerization domain; SAM, sterile α motif; TA, transactivation. (E) Characterization of transcriptional activity of mutant TP73. Data shown are from 3 independent experiments. Error bars represent standard deviation. ***P < .0001.