Figure 1.
Lipidometabolomic signature of AA and SS mouse spleens. (A) Representative multiple reaction monitoring chromatograms, from spleen samples of sickle cell mice exposed to hypoxia (8% oxygen; 10 hours) and followed by reoxygenation (21% oxygen; 3 hours), used to identify LMs. (B) MS/MS fragmentation spectra used for identification of RvD1, LXA4, and PGE2.

Lipidometabolomic signature of AA and SS mouse spleens. (A) Representative multiple reaction monitoring chromatograms, from spleen samples of sickle cell mice exposed to hypoxia (8% oxygen; 10 hours) and followed by reoxygenation (21% oxygen; 3 hours), used to identify LMs. (B) MS/MS fragmentation spectra used for identification of RvD1, LXA4, and PGE2.

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